Unraveling Aging Mysteries through Optogenetic Dissection of ISR Dysregulation
It’s common knowledge that stress can accelerate the aging process, yet how this occurs at the cellular level is not well understood. Dr. Wilson's research incorporates cutting-edge methods to simulate stress in human cells allowing him to mimic any potential stress signal in any cell-type of the human body. Thus, he can pioneer experiments like comparing how cells of different ages react to stress or studying cells under prolonged stress, a condition known to accelerate aging. Dr. Wilson's goal is to unravel how human stress responses change as we age and how they contribute to a variety of age-related diseases such as neurodegeneration and diabetes. Ultimately Dr. Wilson's research seeks to identify genes that help cells cope with harmful stress. These discoveries could lead to new treatments and drugs that modify how humans deal with stress as they age, offering new ways to extend healthy lifespans and fight age-related diseases.
