Advancing Research
by funding Grant Programs and Fellowships
Driving Innovation
by guiding studies such as the FAST Initiative, the SuperAgers Initiative, and the TAME Trial
Furthering the Field
by supporting the infrastructure of three NIA Initiatives and leading the Amplifying Geroscience Initiative.
Top Breakthroughs driven by AFAR Experts
Delaying Disease by Targeting Aging
Saving Costs by Extending Healthspan
What are the Hallmarks of Aging?
What is Geroscience?
What is the Longevity Dividend?
The body becomes increasingly susceptible to infection and chronic inflammatory conditions as it ages. This is attributed to the over-production and age-related reprogramming of circulating white blood cells, known as monocytes, that contribute to low-grade inflammation. In the proposed research, Dr. Deborah Winter will determine how monocyte development is altered in aging. Using a functional genomics approach to map the key factors involved in aging, Dr. Winter’s research will provide potential targets for therapies that can alleviate the negative effects on the immune system caused by aging and enable us to remain healthy as we age.
