Advancing Research
by funding Grant Programs and Fellowships
Driving Innovation
by guiding studies such as the FAST Initiative, the SuperAgers Initiative, and the TAME Trial
Furthering the Field
by supporting the infrastructure of three NIA Initiatives and leading the Amplifying Geroscience Initiative.
Top Breakthroughs driven by AFAR Experts
Delaying Disease by Targeting Aging
Saving Costs by Extending Healthspan
What are the Hallmarks of Aging?
How and Why Do We Age?
What is Geroscience?
What is the Longevity Dividend?
What's Next in aging research?
Sarcopenia, the process of muscles becoming weaker and smaller with age, is a condition that significantly impacts health and quality of life in older adults. Sarcopenia currently has no effective treatment because the mechanisms that cause it are largely unknown. This study examines the hypothesis that it is related to defective calcium handling in aging muscle cells. In the proposed study, Dr. Rizwan Qaisar will investigate how the abnormal processing of muscle calcium by a group of muscle proteins contribute to sarcopenia. The findings from this study will provide new insight into the causes of sarcopenia and assist in developing therapeutic interventions to improve or maintain muscle size and strength in the elderly.
