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The latest updates from AFAR.

Grantee in the News: Ramsey Najm research on Alzheimer’s and the ApoE4 gene in Nature

Apr 18
2018

Grantee in the News: Ramsey Najm research on Alzheimer’s and the ApoE4 gene in Nature

On April 9, 2018, Nature published research co-authored by 2017 Glenn/AFAR Scholarships for Research in the Biology of Aging recipient Ramsey Najm.  In “Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector,” Najm and fellow researchers found that by “using human neurons derived from induced pluripotent stem cells that expressed apolipoprotein E4 (ApoE4), a variant of the APOE gene product and the major genetic risk factor for AD, we demonstrated that ApoE4-expressing neurons had higher levels of tau phosphorylation, unrelated to their increased production of amyloid-β (Aβ)…


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Expert in the News: CoE Officer Rosanne Leipzig in The New York Times on the new Shingles Vaccine

Apr 12
2018

Expert in the News: CoE Officer Rosanne Leipzig in The New York Times on the new Shingles Vaccine

On April 9, 2018, The New York Times’ Personal Health column by Jane Brody highlighted Rosanne Leipzig, M.D., Ph.D., a site officer of the John A. Hartford Foundation’s Center of Excellence in Geriatric Medicine and Geriatric Psychiatry at the Icahn School of Medicine at Mount Sinai in New York City. “Why You Should Get the New Shingles Vaccine,” focuses on the new product Shringrix, which has been shown “to be far more effective at preventing this disease than the first shingles vaccine, Zostavax,” Brody states. The piece notes how common chickenpox was before…


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Awardee in the News: Longo interviewed on NPR on Calorie Restriction and Metabolism

Apr 11
2018

Awardee in the News: Longo interviewed on NPR on Calorie Restriction and Metabolism

On April 2, 2018, NPR interviewed 2013 Vincent Cristofalo Rising Star Award in Aging Research recipient Valter D. Longo, Ph.D. on calorie restriction and metabolism. The segment, “You May Live Longer By Severely Restricting Calories, Scientists Say,” highlights a study by Leanne Redman with fifty-three participants where one group ate their normal meals and the other group was on a calorie restricted diet.  The results were that the group on the calorie restricted diet had a slower and more efficient metabolism and lower blood pressure, cholesterol, and triglycerides. Dr. Longo lends expert insights based on his research on calorie…


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Grantee in the News: Martens research in Nature on Metabolism and Cardiovascular Health

Apr 6
2018

Grantee in the News: Martens research in Nature on Metabolism and Cardiovascular Health

On March 29, 2018, Nature published research co-authored by 2014 Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research grantee, Christopher Martens, Ph.D. In “Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults,” the study presents how “chronic supplementation with the NAD+ precursor vitamin, nicotinamide riboside (NR), is well tolerated and effectively stimulates NAD+ metabolism in healthy middle-aged and older adults.”  Later one of the goals of the study is explained: “an important goal of the present study was to identify clinically relevant physiological outcomes for future larger-scale (phase…


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AFAR Experts in the new PBS Documentary Incredible Aging highlighted in LongevityFacts

Apr 4
2018

AFAR Experts in the new PBS Documentary Incredible Aging highlighted in LongevityFacts

On March 5, 2018, LongevityFacts highlighted AFAR experts in the new PBS documentary Incredible Aging, including: • Steven Austad, Ph.D., AFAR Scientific Director • Nir Barzilai, M.D., AFAR Deputy Scientific Director, 1997 Paul B. Beeson Emerging Leaders Career Development Award in Aging, and 1994 Glenn Foundation for Medical Research and AFAR Grant For Junior Faculty • Judith Campisi, Ph.D., 1990 Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty • Ana Maria Cuervo, M.D., Ph.D., 2008 Vincent Cristofalo Rising Star Award in Aging Research, and 2000 Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty • Matt Kaeberlein,…


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