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News

The latest updates from AFAR.

Grantee in the News: Leora Horwitz in JAMA Internal Medicine on the importance of personal protective equipment and patient safety

Jun 21
2018

Grantee in the News: Leora Horwitz in JAMA Internal Medicine on the importance of personal protective equipment and patient safety

On June 11, 2018, JAMA Internal Medicine published an editorial by 2010 Beeson Scholar Leora Horwitz, M.D. In “The Importance of User-Centered Design and Evaluation,” Dr. Horwitz looks at a qualitative study recently published in JAMA Internal Medicine that found “that errors and lapses in safety while donning, wearing, or doffing PPE (personal protective equipment) were frequent, although not quantified.” Dr. Horwitz comments on the reasons for these violations: “Given the complexity, time intensity, and material waste involved in using PPE, clinicians appeared to be making a deliberate cost-benefit assessment in avoiding PPE use in perceived low-risk…


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Grantee in the News: Domenico Praticò in Molecular Neurobiology on reversing brain damage from dementia in mice

Jun 20
2018

Grantee in the News: Domenico Praticò in Molecular Neurobiology on reversing brain damage from dementia in mice

On June 7, 2018, Molecular Neurobiology published research co-authored by 1997 AFAR Research Grant and 1999 AFAR/Pfizer Innovations in Aging Research Award recipient Domenico Praticò, M.D. In “Learning Impairments, Memory Deficits, and Neuropathology in Aged Tau Transgenic Mice Are Dependent on Leukotrienes Biosynthesis: Role of the cdk5 Kinase Pathway,” Dr. Pratico and his team found that “the first demonstration that the leukotriene biosynthesis is functionally involved at the later stages of the tau pathological phenotype and represents an ideal target with viable therapeutic potential for treating human tauopathies.” In a related article in ScienceAlert, Dr. Praticò…


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Grantee in the News: Reisa Sperling in The Boston Globe on intervening during preclinical stages of Alzheimer’s disease

Jun 18
2018

Grantee in the News: Reisa Sperling in The Boston Globe on intervening during preclinical stages of Alzheimer’s disease

On June 11, 2018, The Boston Globe spotlighted 2003 Beeson Scholar Reisa Sperling, M.D. M.M.Sc. ”Can this doctor figure out how to stop Alzheimer’s before it starts?” spotlights Dr. Sperling’s research on the preclinical phase of Alzheimer’s disease through the buildup of amyloid plaques and tau tangles. The article states: “Sperling thinks early intervention may soon emerge as the treatment of choice for a huge swath of patients. Her work on the preclinical phase over the last decade has led to a new biological definition of Alzheimer’s: one based…


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AFAR Experts in the News: Nathaniel David and Judith Campisi in Forbes on UNITY Biotechnology’s research to target senescent cells

Jun 14
2018

AFAR Experts in the News: Nathaniel David and Judith Campisi in Forbes on UNITY Biotechnology’s research to target senescent cells

On June 5, 2018, Forbes spotlighted AFAR board member Nathaniel David, Ph.D. and 1990 Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty recipient Judith Campisi, Ph.D. “A Biotech Entrepreneur Aims To Help Us Stay Young While Growing Old” focuses on UNITY Biotechnology, a startup co-founded by Nathaniel David and Judith Campisi. The mission of UNITY Biotechnology is to extend human healthspan by using biotechnology and medicine to target age-related diseases. UNITY hopes to develop medicines that remove senescent cells, called senolytics. However, removing senescent cells has not been tested on humans yet. “The problem is…


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Grantee in the News: Kristine Yaffe in WebMD on dementia risk factors

Jun 5
2018

Grantee in the News: Kristine Yaffe in WebMD on dementia risk factors

On May 30, 2018, WebMD highlighted the research and insights of 2001 Paul B. Beeson Emerging Leaders Career Development Award in Aging Scholar recipient Kristine Yaffe, M.D. In “Risk Factors That Put You on The Road to Dementia,” Dr. Yaffe lends her insights on multiple dementia risk factors. “It’s not yet definitive, but in the past 5 years, we’ve made progress on identifying modifiable risk factors for which the evidence is pretty strong,” Dr. Yaffe states. The article spotlights Dr. Yaffe’s co-authored research in JAMA Neurology on mild head injuries and the increased…


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