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The latest updates from AFAR.

Grantee in the News: Ned Sharpless appointed Acting Commissioner of FDA

Mar 14
2019

Grantee in the News: Ned Sharpless appointed Acting Commissioner of FDA

  On March 12, 2019, The New York Times reported that AFAR expert Norman E. (Ned) Sharpless, MD will serve as acting commissioner of the Food and Drug Administration. Dr. Sharpless is a 2003 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar. He also served on AFAR’s National Scientific Advisory Council from 2005-2011 and chaired the Selection Committee of the Glenn/AFAR Postdoctoral Program for Transnational Research on Aging program in 2015 and 2016. Dr. Sharpless has been director of the National Institutes of Health’s National Cancer Institute, since October 2017. He is also chief of the aging biology…


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Grantees in the News: Claire McEvoy and Kristine Yaffe research on dietary patterns and cognition as we age in Neurology and The New York Times

Mar 14
2019

Grantees in the News: Claire McEvoy and Kristine Yaffe research on dietary patterns and cognition as we age in Neurology and The New York Times

  On March 6, 2019, Neurology published research co-authored by AFAR experts Claire T. McEvoy, PhD and Kristine Yaffe, MD on the CARDIA Study, which looked at the impact of dietary patterns during adulthood on cognitive performance in midlife.  The researchers compared the impact of the Mediterranean diet, which involves mainly plant-based foods and moderate alcohol intake; a research-based diet plan that rates food groups as favorable or not; and the DASH diet, which stresses low-sodium foods. Dr. McEvoy is a 2015 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar. Dr. Yaffe is a 2001 Paul B. Beeson…


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Grantee in the News: Guo Huang research in Science on Heart Damage’s link to Hormonal Evolution and Warm Blooded Animals

Mar 11
2019

Grantee in the News: Guo Huang research in Science on Heart Damage’s link to Hormonal Evolution and Warm Blooded Animals

On March 7th, 2019, Science published research by AFAR expert Guo Hung, PhD exploring how in the evolutionary transition from cold to warm blooded animals, humans became more susceptible to heart damage because our thyroid hormones are responsible for stopping cardiac cell division, thus preventing heart tissue from repairing itself after an injury. Dr. Huang received a 2016 AFAR Research Grant for Junior Faculty. Read the published research--“Evidence for hormonal control of heart regenerative capacity during endothermy acquisition” here and related UCSF feature here.  


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Grantees in the News: Sebastian Brandhorst and Valter Longo’s research in Cell Reports on Fasting-Mimicking Diet to Reduce Inflammatory Bowel Disease.

Mar 11
2019

Grantees in the News: Sebastian Brandhorst and Valter Longo’s research in Cell Reports on Fasting-Mimicking Diet to Reduce Inflammatory Bowel Disease.

  On March 5, 2019, Cell Reports published research co-authored by AFAR experts Sebastian Brandhorst,PhD and Valter Longo, MD exploring how a fast-mimicking diet may reduce the effects of Inflammatory Bowel Disease. Fasting primes the body for improvement but it is “re-feeding” that allows cells and tissues to rebuild, their research found. Dr. Brandhorst is a 2017 Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging recipient. Dr. Longo is a 1998 AFAR Research Grant for Junior Faculty recipient and 2013 Vincent Cristofalo Rising Star Award in Aging Research recipient. Read the research—"Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration…


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Experts in the News: Barzilai, Kaeberlein, and Kritchevsky in Kaiser Health News on need for clinical trials for drugs that target aging and disease at once

Mar 8
2019

Experts in the News: Barzilai, Kaeberlein, and Kritchevsky in Kaiser Health News on need for clinical trials for drugs that target aging and disease at once

  On March 6, 2019, Kaiser Health News featured AFAR experts Nir Barzilai, MD, Matt Kaeberlein, PhD, and Steve Kritchevsky, PhD in an article comparing the state of clinical trials for aging-targeting drugs and rising trends in consumer experimentation with these medications. Backed by testimony from these AFAR experts as well as experts from the National Institute of Aging, NIH, the article explains the need for rigorous clinical trials--such as the momentum of AFAR-managed Targeting Aging with Metformin (TAME) Trial--to provide proof-of-concept that safe, cost-effective drugs such as metformin and rapamycin can delay the onset of aging and age-related diseases. Dr. Barzilai…


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