On May 1st, 2024, The Journal of the American Heart Association published research by lead author 2015 AFAR Grantee Jason Hinman, MD, PhD on a new form of assessment for a person’s risk for cerebral small vessel disease and future stroke by using the six molecules in the IL-18 network which could link to a common cause of strokes.
The abstract states:
“A coordinated network of circulating inflammatory molecules centered on the pleotropic pro-atherogenic cytokine interleukin-18 (IL-18) is linked to cerebral small vessel disease. We sought to validate the association of this inflammatory biomarker network with incident stroke risk, cognitive impairment, and imaging metrics in a sample of the Framingham Offspring Cohort.”
This research was advanced in part thanks to The New Investigator Awards in Alzheimer's Disease Dr. Hinman received in 2015.
Read the article “Association of Incident Stroke Risk With an IL-18-Centered Inflammatory Network Biomarker Composite” here.
Read a related press release here.
