2020

Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty

Frederick Bennett, MD

Assistant Professor, University of Pennsylvania School of Medicine

Microglia replacement to understand and treat brain aging

Dr. Bennett’s research focuses on microglia, the brain’s resident immune cell. His AFAR supported research will use transplantation of microglia from one brain to another to dissect the contribution of microglia to brain aging. This research may lead to new treatments for cognitive decline and aging, through direct removal of immune cells from the brain, and their replacement with healthy cells. In other words, Dr. Bennett's studies may provide a proof of concept for cellular therapies to treat brain aging.

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