On May 15, 2023, Aging published a new research paper co-authored by AFAR experts James L. Kirkland, MD, PhD, Laura J. Niedernhofer, MD, PhD, and Nathan K. LeBrasseur, PhD. Their research was featured as the cover story.
In this study, “In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers,” the authors tested multiple complementary approaches to evaluate the possible effects of zoledronic acid—which has been found to reduce fracture risk and, in some studies, extend the lifespan and healthspan of animals—on modulating cellular senescence.
Read the full paper in Aging here.
Dr. Kirkland is AFAR's President, 2020 Irving S. Wright Award of Distinction recipient, 2012 Glenn Foundation for Medical Research Breakthroughs in Gerontology (BIG) Award recipient, and a Professor of Physiology and Professor of Medicine at Mayo Clinic.
Dr. Niedernhofer is an AFAR board member, 2018Vincent Cristofalo Rising Star Award in Aging Research recipient, and the Professor of Biochemistry, Molecular Biology, and Biophysics at the University of Minnesota College of Biological Sciences.
Dr. LeBrasseur is an AFAR 2002 Glenn/AFAR Scholarships for Research in the Biology of Aging recipient, 2019 Vincent Cristofalo Rising Star Award in Aging Research recipient, Director of the Robert and Arlene Kogod Center on Aging at the Mayo Clinic, and the Consultant, Professor, and Co-Chair of Research in the Department of Physical Medicine and Rehabilitation at the Mayo Clinic.
