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AFAR in the News: AFAR leadership in Nature piece on the clinical trial potential of drugs targeting age-related diseases

On June 17, 2015, Nature journal spotlighted the Targeting Aging with Metformin (TAME) Trial spearheaded by AFAR Deputy Scientific Director Dr. Nir Barzilai and explored its larger implications for aging research.

On June 24th, Dr. Barzilai will lead a group meeting to engage the FDA in a discussion about recognizing aging as an indication that is appropriate for clinical trials. If successful, the TAME Trial could prove that a drug targeting aging can be an effective method of delaying the onset of aging-related diseases, including cancer, heart disease, and cognitive impairment.

As AFAR’s executive director, Stephanie Lederman, notes in the piece: “The perception is that we are all looking for a fountain of youth, we want to avoid that; what we’re trying to do is increase health span, not look for eternal life.”
AFAR has helped facilitate the planning process for this high-level meeting.

The article, which also featured insight from two-time grantee Dr. Matt Kaeberlein, can be viewed here.

Uniquely, this story has generated buzz beyond the aging research field, as it’s been picked up by lifestyle blog Refinery29 and the Nigerian news source AllAfrica.

Nir Barzilai, MD,is a Professor in the Albert Einstein College of Medicine Departments of Medicine and Genetics, the Ingeborg and Ira Leon Rennert Chair in Aging Research, and the Director of the college’s Institute for Aging Research.

Matt Kaeberlein, PhD, is an Associate Professor at the University of Washington.

For over 30 years, AFAR has supported 3000 investigators at more than 500 leading institutions nationwide through over $147 million in grant awards--all to advance research that will extend healthspan, the time we are in optimal health as we age. Learn more about our commitment to improving healthspan here.

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