On July 31, 2023, Nature Communications published new research co-authored by AFAR’s 2021 Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research recipient Madison Doolittle, PhD, defining cells in the bone microenvironment that are most susceptible to developing age-related cellular senescence.
Identification of these causal senescent cells may uncover mechanisms of bone loss and may allow for cell-specific therapies for the modulation of aging and osteoporosis, the research poses.
Read the full paper, 'Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton,' here.
Dr. Doolittle is a Research Associate at the Mayo Clinic Department of Endocrinology, Diabetes, Metabolism and Nutrition. Learn more about Dr. Doolittle’s AFAR-supported research here.
