The neural origins of exercise intolerance in the aging human: implications for widening the healthspan
With age, it becomes progressively more difficult to perform and engage in regular physical activity. This difficulty may be due to an increasing intensity of symptoms of like breathlessness and fatigue. In the proposed research, Dr. Troy Cross will investigate how neural information arising from breathing and limb muscles may be involved in the increased perceptions of breathlessness/limb fatigue that we observe with advancing age. This research has the potential to identify new therapeutic targets to reduce breathlessness and limb discomfort during physical activity, and may offer a way to break out of the deconditioning spiral of human aging.