Advancing Research
by funding Grant Programs and Fellowships
Driving Innovation
by guiding studies such as the FAST Initiative, the SuperAgers Initiative, and the TAME Trial
Furthering the Field
by supporting the infrastructure of three NIA Initiatives and leading the Amplifying Geroscience Initiative.
Top Breakthroughs driven by AFAR Experts
Delaying Disease by Targeting Aging
Saving Costs by Extending Healthspan
What are the Hallmarks of Aging?
What is Geroscience?
What is the Longevity Dividend?
The mechanisms that underlie the exceptional longevity of nerve cells in our brain (>90 years) remain unclear. If they were understood, however, they could be targeted to restore nerve cell function in the context of aging and neurodegeneration, and they could also potentially be induced in other cell types of the body to increase the healthspan of the whole organism. In this project we purpose to conduct a rigorous and unbiased testing in the mammalian nervous system of genes that we predict to be able to restore aging-associated decline in nerve cells.
