2018 Grant Recipients

 

Biology of Aging Grants
 

Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty


New Investigator Awards in Alzheimer's Disease
 

Glenn Foundation for Medical Research Breakthroughs in Gerontology (BIG) Award
 

Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research
 

Scholarships for Research in the Biology of Aging


The Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging

 

Physician Training Grants

 

The Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76)

 

Medical Student Training in Aging Research (MSTAR) Program

 


 

Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty

Joshua Baker, MD, MSCE, Assistant Professor of Medicine, University of Pennsylvania: Age and Obesity-related Alterations in Skeletal Muscle Mitochondrial Activity and Lipid Distribution, and Associations with Joint Inflammation and Cartilage Degeneration in Osteoarthritis
Daniel Berry, PhD, Assistant Professor, Cornell University: Age-dependent Decline of Beige Adipocyte Induction and its Metabolic Consequences
Benjamin Cosgrove, PhD, Assistant Professor, Cornell University: Single-cell Dissociation of Muscle Stem Cell Dysfunction in Human Aging
Isha Jain, PhD, University of California, San Francisco, Sandler Faculty Fellow, University of California, San Francisco: Hypoxia as a Therapy for Age-associated Proteotoxic Stress and Neurodegeneration
Kishore Kuchibhotla, PhD, Assistant Professor, Johns Hopkins University: Improving Cognitive Flexibility in Aging by Modulating Context-dependent Neural Circuits
Po-Ru Loh, PhD, Assistant Professor, Brigham and Women's Hospital / Harvard Medical School: Understanding the Etiology and Effects of Age-related Clonal Hematopoiesis
Andreas Pfenning, PhD, Assistant Professor, Carnegie Mellon University: Cell Type-specific Epigenetic Decay Underlying Brain Aging
Andrew Pickering, PhD, Assistant Professor, University of Texas Health Science Center at San Antonio: Determine if Genetic and Pharmacologic Proteasome Manipulation Can Prevent Age-related Cognitive Deficits in Mice and Flies
Vivek Venkatachalam, PhD, Assistant Professor, Northeastern University: Whole Brain Dynamics in Aging C. Elegans
Kevin Wang, MD, PhD, Assistant Professor, Stanford University School of Medicine: Rebooting the Nuclear Architecture as an Innovative Cellular Reprogramming Strategy to Reverse Aging
Deborah Winter, PhD, Assistant Professor, Northwestern University, Feinberg School of Medicine: Uncovering the Role of Epigenomic Reprogramming on Monocyte Development in Aging
Nilay Yapici, PhD, Assistant Professor, Cornell University: Deciphering Changes in the Structure and Function of Neural Circuits that Regulate Homeostatic Drives During Aging

 

Glenn Foundation for Medical Research Breakthroughs in Gerontology (BIG) Award

Peter Adams, PhD, Professor, Sanford-Burnham Prebys Medical Discovery Institute: Testing the role of barriers to reprogramming in chromostasis and longevity
M. Brandon Westover, MD, PhD, Associate Professor of Neurology, Massachusetts General Hospital: Electroencephalogram-based Brain Age and its Relation with Cognitive Function and Sleep Quality

 

Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research

Joel Blanchard, PhD, Postdoctoral Associate, Massachusetts Institute of Technology: Understanding Myelin Degeneration in Alzheimer's Disease and Aging
Jorge Castillo-Quan, MD, PhD, Research Fellow, Harvard University: Elucidating pathways by which lipid signals modulate longevity, redox metabolism and proteostasis
Ukrae Cho, PhD, Research Associate, The Salk Institute for Biological Studies: Linking long-lived protein maintenance, nuclear protein homeostasis, and brain aging
Ching-Chieh Chou, PhD, Postdoctoral Research Fellow, Stanford University: Systematic dissection of the protein homeostasis network affected by aging and neurodegenerative diseases using human neuronal models
Susan Eliazer, PhD, Postdoctoral Fellow, University of California, San Francisco: Wnt4 as a novel therapeutic for rejuvenating muscle stem cell function during aging
Karl Miller, PhD, Postdoctoral Associate, Sanford-Burnham Prebys Medical Discovery Institute: Mitochondrial retrograde signaling as a therapeutic target for senescence-associated inflammation
Sean James Miller, PhD, Postdoctoral Fellow, Stanford University School of Medicine: Investigating the effects of Norrin on the blood-brain-barrier
Sharon Owino, PhD, MSCR, Postdoctoral Fellow, Emory University: The role of GPR37 in Alzheimer's disease pathogenesis
Jyung Mean Son, PhD, Postdoctoral Scholar, University of Southern California: Nuclear gene regulation by the mitochondrial-encoded peptide MOTS-c during aging
Kristoffer Svensson, PhD, Postdoctoral Researcher University of California, San Diego: Protein acetylation and age-related skeletal muscle contractile dysfunction
Stephen Treaster, PhD, Postdoctoral Fellow, Boston Children's Hospital: Leveraging natural experiments in aging through broad phylogenetic analysis of genomic variation

AFAR is grateful to the Glenn Foundation for Medical Research for their support of and collaboration on the above grant programs.


New Investigator Awards in Alzheimer's Disease

Xiaobo Mao, PhD, Assistant Professor, Johns Hopkins University: The role of TTR1/2 in mediating tau spreading and therapeutic strategy development
Andrea Soranno, PhD, Assistant Professor, Washington University in St. Louis: Identifying neurotoxic conformers in the structural ensemble of ApoE
Vivek Swarup, PhD, Assistant Professor, University of California, Irvine: A functional genomics approach to identify neuronal and glial regulators of neurodegeneration

AFAR is grateful to The Rosalinde and Arthur Gilbert Foundaton for their support of and collaboration on this program.


 

The Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging

Bumsoo Ahn, PhD, Postdoctoral Fellow, Oklahoma Medical Research Foundation: Unacylated ghrelin as a therapeutic strategy for age-associated skeletal muscle weakness
Jenna Bartley, PhD, Postdoctoral Fellow, University of Connecticut School of Medicine: The effect of metformin on influenza vaccine responses and T cell function in the elderly
John Collins, PhD, Postdoctoral Fellow, University of North Carolina at Chapel Hill: SIRT6 as a novel therapeutic target in aging and osteoarthritis
Troy Cross, PhD, Senior Research Fellow, Mayo Clinic: The neural origins of exercise intolerance in the aging human: implications for widening the healthspan
Shelli Farhadian, MD, PhD, Postdoctoral Fellow, Yale University School of Medicine: Neuroinflammation in older adults with HIV: A single cell approach
Amy Gleichman, PhD, Postdoctoral Fellow, University of California, Los Angeles: Astrocytic regulation of synapse formation and elimination in aged mice after stroke
Claire Gustafson, PhD, Postdoctoral Fellow, Stanford University: T Follicular Helper Cells in Mucosal Immune Aging
Emilie Reas, PhD, Postdoctoral Fellow, University of California, San Diego: Association between Blood-Brain Barrier Braekdown and Brain Microstructure in Mild Cognitive Impairment


 

Scholarships for Research in the Biology of Aging

Andree-Anne Berhiaum, Seattle Children's Research Insitute/The Medical University of South Carolina: Pericyte structural plasticity in the aging mouse brain: An in vivo two-photon imaging study
Ryan Castro, Virginia Polytechnic Institute and State University: Age-related changes in microglia activity in the mouse spinal cord
Michael Cooney, Harvard University: Enhancing genomic stability with exogenous DNA repair proteins to uncover the connection between genomic and epigenomic stability during aging
Albina Ibrayeva, University of Southern California/The Buck Institute for Research on Aging: Defining and reversing neural stem cell aging
Andrew Kane, Harvard University: Examining the role of Hsf1 in age-related aggregation and lifespan
Gavin Pharaoh, University of Oklahoma Health Sciences Center: Understanding the role of muscle lipid hydroperoxides in the initiation and progression of muscle atrophy
Jason Wan, Georgia Institute of Technology: Engineering a novel microfluidic platform for high-throughput cellular resolution smFISH analysis of gene expression in whole organisms
Xiaotian Wu, Brown University: Penalized Latent Dirichlet Allocation Model for Aging Single Cell RNA Sequencing Data

 


 

The Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76)

Rebecca Brown, MD, MPH, Assistant Professor of Medicine, University of Pennsylvania: Improving aging in place for older adults living in subsidized housing
Kathryn Callahan, MD, Assistant Professor, Wake Forest School of Medicine: Identifying Frailty in Primary Care: Implementation of an Electronic Medical Recotrd-Based Frailty Index
Andrew Cohen, MD, DPhil, Assistant Professor of Internal Medicine (Geriatrics), Yale University: Dementia and Decision-Making for Older Adults without Surrogates
Guido Falcone, MD, ScD, MPH, Assistant Professor of Neurology, Yale School of Medicine: Genetic analyses of radiological severity, short-term functional outcome and long-term health status in spontaneous intracerebral hemorrhage
Andrea Gilmore-Bykovskyi, PhD, RN, Assistant Professor, University of Wisconsin-Madison: Novel Approaches to Identifying and Engaging Disadvantaged Patients with Alzheimer's Disease (AD) in Clinical Research
Rasheeda Hall, MD, Assistant Professor of Medicine, Duke University Medical Center: Deprescribing for Older Dialysis Patients
Biren Kamdar MD, MBA, MHS, Assistant Clinical Professor, University of California, San Diego School of Medicine: Multicomponent Intervention to Improve Delirium and Sleep-Wake Rhythms in Older ICU Patients
Jennifer Portz, PhD, MSW, Assistant Professor, Coloardo State University: Social Convoy Palliative Care (Convoy-Pal) Mobile Health for Older Adults with Advanced Heart Failure
Nancy Schoenborn, MD, Assistant Professor of Medicine, Johns Hopkins University: Improving Cancer Screening in Older Adults with Limited Life Expectancy
Indranil Sinha, MD, Assistant Professor of Surgery, Harvard Medical School/Brigham and Women's Hospital: Aging-Associated Dysregulation of the Hypoxia Pathway Limits Skeletal Muscle Regeneration

 


 

Medical Student Training in Aging Research (MSTAR) Program

MSTAR Students Privately Funded at Weill Cornell Medical College

Sarah Dion, University of Cincinnati College of Medicine
James Gang, Weill Cornell Medical College
Max Morin, Weill Cornell Medical College
Tatiana Requijo,Weill Cornell Medicine





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