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Grantees in the News: Research co-authored by 3 AFAR grantees on stem cell adaptation in homeostasis and injury in Cell

On August 22, Cell published research by AFAR experts Chia-Wei Cheng, PhD, Maria Mihaylova, PhD, and Ömer H. Yilmaz, MD, PhD that finds that control of βOHB-activated signaling in ISCs by diet helps to fine-tune stem cell adaptation in homeostasis and injury.

Dr. Cheng is a 2019 Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging recipient and a Postdoctoral Fellow at the Koch Institute for Integrative Cancer Research at MIT.

Dr. Mihaylova is a 2019 AFAR Research Grant recipient and an Assistant Professor at the Ohio State University.

Dr. Yilmaz is a 2015 AFAR Research Grant recipient, and a Eisen and Change Career Development Professor and Associate Professor of Biology at the Koch Institute for Integrative Cancer Research at MIT.

Read the research, “Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet,” here.

Read a press release from MIT on the research, “Study links certain metabolites to stem cell function in the intestine,” here.

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