News

< Back

Grantee in the News: Reisa Sperling, MD, Calls for Drug Testing Earlier in Alzheimer's Disease

On November 30, The Boston Globe reported on a paper published by grantee Reisa Sperling, MD, MMSc, in Science Translational Medicine, which called for subjects with less advanced Alzheimer’s disease in drug trials. Dr. Sperling and her colleagues made the case that the failure of recent trials of drugs targeting the build-up of plaques in the brain that characterizes Alzheimer’s may be because the subjects in the trials, who had advanced Alzheimer’s, have already undergone too much damage for a benefit to be detectable. Dr. Sperling is designing a trial in which subjects with plaque accumulation, but without the level of cognitive impairment normally used to diagnose Alzheimer’s, will test potential Alzheimer’s treatments. Dr. Sperling is Associate Professor of Neurology at Harvard Medical School, Department of Neurology and Brigham and Women's Hospital, and a recipient of a 2003 Paul B. Beeson Career Development Award in Aging Research Program.

More Recent News

View All News >
Encouraged by AFAR Amplifying Geroscience Initiative, Congress is directing NIH to tabulate annual spending on geroscience research.
Encouraged by AFAR Amplifying Geroscience Initiative, Congress is directing NIH to tabulate annual spending on geroscience research.
Grantee News: 2022 McKnight Brain Research Foundation Innovator Awards in Cognitive Aging and Memory Loss recipient Tara Tracy, PhD featured as one “next generation of biotech superstars”; publishes research on new strategies for addressing Alzheimer’s and dementia-related memory problems
Grantee News: 2022 McKnight Brain Research Foundation Innovator Awards in Cognitive Aging and Memory Loss recipient Tara Tracy, PhD featured as one “next generation of biotech superstars”; publishes research on new strategies for addressing Alzheimer’s and dementia-related memory problems
AFAR Grantee in the News: New Research by Ömer Yilmaz on the SOX 17 gene and its contributions to Colon cancer detection was published in Nature.
AFAR Grantee in the News: New Research by Ömer Yilmaz on the SOX 17 gene and its contributions to Colon cancer detection was published in Nature.
In Memoriam: Marc Weksler, MD, former AFAR Board President
In Memoriam: Marc Weksler, MD, former AFAR Board President
In Memoriam: Norman Volk, Former AFAR Board Member
In Memoriam: Norman Volk, Former AFAR Board Member
AFAR Grantee in the News: New Research by AFAR Grantee Aditi Gurkar on the molecular index of biological aging published in Aging Cell.
AFAR Grantee in the News: New Research by AFAR Grantee Aditi Gurkar on the molecular index of biological aging published in Aging Cell.
AFAR Grantee in the News: New Research by Dibyadeep Datta on a biomarker that could indicate ensuing Alzheimer's disease published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association
AFAR Grantee in the News: New Research by Dibyadeep Datta on a biomarker that could indicate ensuing Alzheimer's disease published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association
AFAR Grantee in the News: New Research by Mark E. Kleinman on histone dynamics, cellular senescence, and aging in Aging Cell.
AFAR Grantee in the News: New Research by Mark E. Kleinman on histone dynamics, cellular senescence, and aging in Aging Cell.
AFAR News: Gareth W. Shepherd, PhD, and Robert W. Stearns elected to Board of Directors
AFAR News: Gareth W. Shepherd, PhD, and Robert W. Stearns elected to Board of Directors