Grantee in the News: Martens research in Nature on Metabolism and Cardiovascular Health
On March 29, 2018, Nature published research co-authored by 2014 Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research grantee, Christopher Martens, Ph.D.
In “Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults,” the study presents how “chronic supplementation with the NAD+ precursor vitamin, nicotinamide riboside (NR), is well tolerated and effectively stimulates NAD+ metabolism in healthy middle-aged and older adults.”
Later one of the goals of the study is explained: “an important goal of the present study was to identify clinically relevant physiological outcomes for future larger-scale (phase II) clinical trials of NR supplementation. The most promising result of these exploratory analyses was a trend towards an improvement in selective indicators of cardiovascular function. Compared with placebo, NR tended to lower SBP and aortic stiffness, two major independent risk factors for incident cardiovascular events and disease with advancing age, in the overall group.”
Read the research here.
Christopher Martens, Ph.D. is a Postdoctoral Fellow at the University of Colorado Boulder.