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Grantee in the News: Jason Karlawish research on heightened amyloid levels in JAMA Neurology

Oct 31
2017

Grantee in the News: Jason Karlawish research on heightened amyloid levels in JAMA Neurology View MoreBACK

On October 23, 2017, JAMA Neurology published research co-authored by 2007 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar Jason Karlowish, MD, on the impact that knowledge on amyloid protein plaque levels had on cognitively normal older patients at higher risk of Alzheimer’s.

As explained in a related press release from the Perelman School of Medicine at the University of Pennsylvania notes, the published research,  “Comprehension of an Elevated Amyloid Positron Emission Tomography Biomarker Result by Cognitively Normal Older Adults”:  examined cognitively normal adults 65 years and older who had been accepted into a large Alzheimer's prevention trial based on brain scans showing an "elevated" level of beta amyloid protein plaques. Beta Amyloid plaques are one of the biomarkers of Alzheimer's-disease. The researchers found that for many of these seniors, being told that that their amyloid levels were "elevated" on brain scans led to frustration and a desire for more detailed information.

Read the study here.

Read the related press release here.


Jason Karlawish, MD is a Professor of Medicine, Medical Ethics and Health Policy, and Neurology at the University of Pennsylvania Perelman School of Medicine and the Co-Director of the Penn Memory Center.
 





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