News
News

The latest updates from AFAR.

Grantee in the News: Domenico Praticò’s research on tau pathology and metabolic risk factor for neurodegenerative disease in Nature’s Molecular Psychiatry

May 22
2018

Grantee in the News: Domenico Praticò’s research on tau pathology and metabolic risk factor for neurodegenerative disease in Nature’s Molecular Psychiatry View MoreBACK

On May 4, 2018, Nature’s Molecular Psychiatry published research co-authored by 1997 AFAR Research Grant and 1999 AFAR/Pfizer Innovations in Aging Research Award recipient Domenico Praticò, M.D.

In “Elevated levels of brain homocysteine directly modulate the pathological phenotype of a mouse model of tauopathy,” Dr. Praticò and his peer authors found that “our findings support the novel concept that high Hcy level in the central nervous system is a metabolic risk factor for neurodegenerative diseases, specifically characterized by the progressive accumulation of tau pathology, namely tauopathies.”

The research is available by subscription-only here, but a related press release can be read here.


Domenico Praticò, M.D. is a Professor of Pharmacology and Microbiology and Immunology at the Center for Translational Medicine at the Lewis Katz School of Medicine at Temple University.





View MoreBACK TO TOP