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Experts in the News: Rudy Tanzi and Wilma Wasco research suggests ATXN1 can be used to delay the onset of Alzheimer’s disease in Cell

Aug 29
2019

Experts in the News: Rudy Tanzi and Wilma Wasco research suggests ATXN1 can be used to delay the onset of Alzheimer’s disease in Cell View MoreBACK

On August 22, Cell published research co-authored by AFAR experts Rudolph E. Tanzi, PhD, and AFAR expert Wilma Wasco, PhD, on how the gene ATXN1 can regulate the behavior of the enzyme ataxin-1 and decrease the risk for Alzheimer’s disease. This discovery may help to identify new targets for experimental medications designed to delay or stop the onset of Alzheimer’s disease.

Dr. Tanzi is a member of AFAR’s Board of Directors. He is also the Director of the Genetics and Aging Research Unit at Massachusetts General Institute for Neurodegenerative Disease, and a Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School.

Dr. Wasco is a 1993 AFAR Research Grant recipient, as well as the Associate Professor of Neurology at Harvard Catalyst and the Associate Geneticist at Massachusetts General Hospital.

Read the research, “Loss of Ataxin-1 Potentiates Alzheimer’s Pathogenesis by Elevating Cerebral BACE1 Transcription,” here.

Read a press release on the research from Massachusetts General Hospital, “Mass General Hospital researchers discover that a gene linked to a rare neurological disorder also regulates a Key enzyme involved in Alzheimer’s disease,here.





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