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Experts in the News: James Kirkland and Ming Xu on how transplant cells from old donors cause physical dysfunction in AFAR-funded research in Aging Cell

Feb 10
2020

Experts in the News: James Kirkland and Ming Xu on how transplant cells from old donors cause physical dysfunction in AFAR-funded research in Aging Cell View MoreBACK

On January 23, 2020, Aging Cell published research by AFAR experts James L. Kirkland, MD, PhD, and Ming Xu, PhD, which finds that transplanting Adipose‐derived mesenchymal (ADSC) stem cells from old donors creates a senescent cell-like population and induces physical dysfunction in older mice recipients.

Dr. Kirkland is AFAR’s President-Elect and a 2012 Glenn Foundation for Medical Research Breakthroughs in Gerontology (BIG) Award recipient. He is also a distinguished Professor of Medicine and Physiology, as well as the Director at the Robert and Arlene Kogod Center on Aging at the Mayo Clinic College of Medicine.

Dr. Xu is a 2019 Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty recipient and a 2014 Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging recipient. He is also an Assistant Professor at the UConn Center on Aging and the Department of Genetics and Genome Sciences at the University of Connecticut.

The research was funded in part by Dr. Xu’s Postdoctoral Award and his Glenn Foundation/AFAR Grant for Junior Faculty.

Read the research, “Transplanting cells from old but not young donors causes physical dysfunction in older recipients,” here.





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