On November 14,2017, MedicalXpress reported on research authored by Board Member and two time grantee Thomas Rando, MD, PhD in the November 14 issue of Cell Reports on muscle stem cells.
In the article, “Stem cells express genes differently in the lab dish than in the body, study finds”, MedicalXPress notes:
The research suggests that any conclusions about stem cell function based on studies of isolated stem cells may now need to be reconsidered in light of the fact that the cells' biology changes during isolation.
The results confirmed what previous research in Rando's laboratory has shown: Despite their seemingly sleepy lifestyle, muscle stem cells are actually hotbeds of activity concealed by a tranquil outer membrane.
Read more here.
Read the original research, "Transcriptional Profiling of Quiescent Muscle Stem Cells In Vivo," published in Cell Reports here.
Thomas A. Rando, MD, PhD, is the Principal Investigator of the Thomas Rando Lab at Stanford University, where he is also the Director of the Glenn Center for the Biology of Aging, Deputy Director of the Stanford Center on Longevity, and a Professor in the Department of Neurology and Neurological Sciences.
Dr. Rando is a 1999 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar and a 2008 Glenn/AFAR Breakthroughs in Gerontology Award winner.
