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Awardees in the News: Rozalyn Anderson and Rafael de Cabo co-author Caloric Restriction Study

Jan 20
2017

Awardees in the News: Rozalyn Anderson and Rafael de Cabo co-author Caloric Restriction Study View MoreBACK

2016 Glenn/AFAR Breakthroughs in Gerontology (BIG) Award winner Rozalyn Anderson, PhD, and 2014 Vincent Cristofalo Rising Star Award in Aging Research winner Rafael de Cabo, PhD, are among the co-authors of a collaborative study on caloric restriction and aging published in Nature Communications online on January 17, 2017.

By focusing on the rhesus monkey as an excellent model for human aging due to genetic similarities and rates of aging,  “Caloric restriction improves health and survival of rhesus monkeys” presents insights that the health benefits from caloric restriction could apply to humans.

The collaborative article examines data from two studies by teams teams at the University of Wisconsin and National Institute on Aging.

As the authors note in Nature Communications:

We present a direct comparison of longitudinal data from both studies including survival, bodyweight, food intake, fasting glucose levels and age-related morbidity. We describe differences in study design that could contribute to differences in outcomes, and we report species specificity in the impact of Caloric Restriction (CR) in terms of optimal onset and diet.

Taken together these data confirm that health benefits of CR are conserved in monkeys and suggest that CR mechanisms are likely translatable to human health.

 

Read the published study here.

Additionally, TechTimes has reported on the results.

In a related article on The Verge, AFAR Scientific Director Steven Austad weighs in on moving this study to human testing.

Rozalyn Anderson, PhD, is an Assistant Professor in the University of Wisconsin School of Medicine and Public Health Department of Medicine.
 

Raphael de Cabo, PhD, is Senior Investigator and Chief, Translational Gerontology Branch and Chief, Experimental Gerontology Section, at the National Institute on Aging.


For expert insights, read AFAR’s InfoAging guide on Caloric Restriction.





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