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News

The latest updates from AFAR.

Board Member in the News: Steve Austad's latest Next Avenue column explores biological gender differences and longevity

Mar 29
2019

Board Member in the News: Steve Austad's latest Next Avenue column explores biological gender differences and longevity

  On March 27, 2019 Next Avenue published the latest column by AFAR Scientific Director Steven N. Austad, PhD. "What Biology Tells Us About Gender and Longevity” explores research that shows, from hormones to chromosomes, biological differences between men and women reveal fascinating paths to better understanding of longevity at any age. The article spotlights research led by AFAR grantees Emily S. Davis, Dena Dubal, MD, PhD, and Dudley Lamming, PhD as well as Dr. Austad's own published studies. Read Dr. Austad’s column here.  


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Grantees in the News: Research by 7 AFAR grantees in Aging Cell shows how removing senescent cells alleviates causes of diabetes

Mar 28
2019

Grantees in the News: Research by 7 AFAR grantees in Aging Cell shows how removing senescent cells alleviates causes of diabetes

  On March 25, 2019, Aging Cell published research co-authored by AFAR experts Judy Campisi, PhD, Eduardo Chini, MD, PhD, James L. Kirkland MD, PhD, Nathan LeBrasseur, PhD, Allyson Palmer, M.D, PhD, Marissa Schafer, PhD, and Ming Xu, PhD exploring how removal of senescent 'zombie cells' alleviates causes of diabetes in obese mice. The research shows that senolytic drugs hold promise as a treatment of age-related disease. Dr. Campisi is a 2009 AFAR Grant for Junior Faculty recipient. Dr Chini is a 2007 Glenn Foundation for Medical Research Breakthroughs in Gerontology (BIG) Award recipient. Dr. Kirkland MD, PhD is AFAR’s President-Elect…


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Board Member in the News: Steven Austad and TAME Trial in STRIA news

Mar 27
2019

Board Member in the News: Steven Austad and TAME Trial in STRIA news

  On March 25, 2019, STRIA News spotlighted AFAR expert Steven N. Austad, PhD in an article exploring geroscience as research path to help us live healthier, for longer. The article also explores the AFAR-managed Targeting Aging with Metformin (TAME) Trial. Dr. Austad is AFAR’s Scientific Director and serves as co-PI of the Coordinating Center of the Nathan Shock Centers of Excellence in the Basic Biology of Aging of the National Institute of Aging, NIH. Read the article—"Scientists Think They Can Offer Us More Healthy Years. Now What?’’—here.  


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Board Member in News: Nir Barzilai and the TAME Trial featured on CNBC

Mar 27
2019

Board Member in News: Nir Barzilai and the TAME Trial featured on CNBC

  On March 23, 2019, CNBC featured AFAR expert Nir Barzilai, MD and the AFAR-managed Targeting Aging with Metformin (TAME) trial in an article exploring the potential for metformin and other drug interventions to delay the onset of age-related diseases. The article also examines how this potential is influencing consumer behavior, particularly in Silicon Valley. Dr. Barzilai is AFAR’s Deputy Scientific Director, a multiple AFAR grantee, and Director of the Nathan Shock Center of Excellence in the Basic Biology of Aging at Albert Einstein College of Medicine, for which AFAR serves as the coordinating center. Read “Silicon Valley techies…


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Board Members in the News: Nir Barzilai and Jim Mellon in Forbes on biotech opportunities to extend healthspan

Mar 25
2019

Board Members in the News: Nir Barzilai and Jim Mellon in Forbes on biotech opportunities to extend healthspan

  On March 21, 2019, Forbes spotlighted AFAR experts Nir Barzilai, MD, and Jim Mellon in an article exploring biotech opportunities to extend healthspan, including the AFAR-managed TAME (Targeting Aging with Metformin) Trial. Dr. Barzilai is AFAR’s Deputy Scientific Director, a multiple grantee, and Director of the Nathan Shock Center at Einstein Medical College, for which AFAR serves as the coordinating center. Mr. Mellon is an AFAR Board member and recipient of our 2018 George E. and Mary J. Doty Award recipient. The article also mentions research and interventions by 2015 Irving S. Wright Award winner Leonard Guarente, PhD. Read “Opportunities…


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Grantees in the News: Cynthia Carlsson, Dena Dubal, and Ozioma Okonkwo research on KHLOTHO Longevity Gene and Alzheimer’s in Neurology

Mar 25
2019

Grantees in the News: Cynthia Carlsson, Dena Dubal, and Ozioma Okonkwo research on KHLOTHO Longevity Gene and Alzheimer’s in Neurology

On March 13, 2019, Neurology published research co-authored by AFAR experts Cynthia M. Carlsson, MD, MS, Dena Dubal, MD, PhD, and Ozioma C. Okonkwo, PhD on the influence of  KLOTHO gene on Alzheimer's and age-related disease. Dr. Carlsson is a 2005 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar, former Beeson Advisory Committee member, and former John A. Hartford Centers of Excellence Fellow. Dr. Dubal is a  2015 AFAR Research Grant for Junior Faculty recipient, 2009 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar, and 1998 Glenn/AFAR Scholarships for Research in the Biology of Aging recipient. …


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Grantee in the News: Ned Sharpless appointed Acting Commissioner of FDA

Mar 14
2019

Grantee in the News: Ned Sharpless appointed Acting Commissioner of FDA

  On March 12, 2019, The New York Times reported that AFAR expert Norman E. (Ned) Sharpless, MD will serve as acting commissioner of the Food and Drug Administration. Dr. Sharpless is a 2003 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar. He also served on AFAR’s National Scientific Advisory Council from 2005-2011 and chaired the Selection Committee of the Glenn/AFAR Postdoctoral Program for Transnational Research on Aging program in 2015 and 2016. Dr. Sharpless has been director of the National Institutes of Health’s National Cancer Institute, since October 2017. He is also chief of the aging biology…


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Grantees in the News: Claire McEvoy and Kristine Yaffe research on dietary patterns and cognition as we age in Neurology and The New York Times

Mar 14
2019

Grantees in the News: Claire McEvoy and Kristine Yaffe research on dietary patterns and cognition as we age in Neurology and The New York Times

  On March 6, 2019, Neurology published research co-authored by AFAR experts Claire T. McEvoy, PhD and Kristine Yaffe, MD on the CARDIA Study, which looked at the impact of dietary patterns during adulthood on cognitive performance in midlife.  The researchers compared the impact of the Mediterranean diet, which involves mainly plant-based foods and moderate alcohol intake; a research-based diet plan that rates food groups as favorable or not; and the DASH diet, which stresses low-sodium foods. Dr. McEvoy is a 2015 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar. Dr. Yaffe is a 2001 Paul B. Beeson…


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Grantee in the News: Guo Huang research in Science on Heart Damage’s link to Hormonal Evolution and Warm Blooded Animals

Mar 11
2019

Grantee in the News: Guo Huang research in Science on Heart Damage’s link to Hormonal Evolution and Warm Blooded Animals

On March 7th, 2019, Science published research by AFAR expert Guo Hung, PhD exploring how in the evolutionary transition from cold to warm blooded animals, humans became more susceptible to heart damage because our thyroid hormones are responsible for stopping cardiac cell division, thus preventing heart tissue from repairing itself after an injury. Dr. Huang received a 2016 AFAR Research Grant for Junior Faculty. Read the published research--“Evidence for hormonal control of heart regenerative capacity during endothermy acquisition” here and related UCSF feature here.  


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Grantees in the News: Sebastian Brandhorst and Valter Longo’s research in Cell Reports on Fasting-Mimicking Diet to Reduce Inflammatory Bowel Disease.

Mar 11
2019

Grantees in the News: Sebastian Brandhorst and Valter Longo’s research in Cell Reports on Fasting-Mimicking Diet to Reduce Inflammatory Bowel Disease.

  On March 5, 2019, Cell Reports published research co-authored by AFAR experts Sebastian Brandhorst,PhD and Valter Longo, MD exploring how a fast-mimicking diet may reduce the effects of Inflammatory Bowel Disease. Fasting primes the body for improvement but it is “re-feeding” that allows cells and tissues to rebuild, their research found. Dr. Brandhorst is a 2017 Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging recipient. Dr. Longo is a 1998 AFAR Research Grant for Junior Faculty recipient and 2013 Vincent Cristofalo Rising Star Award in Aging Research recipient. Read the research—"Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration…


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Experts in the News: Barzilai, Kaeberlein, and Kritchevsky in Kaiser Health News on need for clinical trials for drugs that target aging and disease at once

Mar 08
2019

Experts in the News: Barzilai, Kaeberlein, and Kritchevsky in Kaiser Health News on need for clinical trials for drugs that target aging and disease at once

  On March 6, 2019, Kaiser Health News featured AFAR experts Nir Barzilai, MD, Matt Kaeberlein, PhD, and Steve Kritchevsky, PhD in an article comparing the state of clinical trials for aging-targeting drugs and rising trends in consumer experimentation with these medications. Backed by testimony from these AFAR experts as well as experts from the National Institute of Aging, NIH, the article explains the need for rigorous clinical trials--such as the momentum of AFAR-managed Targeting Aging with Metformin (TAME) Trial--to provide proof-of-concept that safe, cost-effective drugs such as metformin and rapamycin can delay the onset of aging and age-related diseases. Dr. Barzilai…


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Grantee in the News: Kristine Yaffe on strategies for maintaining cognitive health in New York Times' New Old Age column

Mar 08
2019

Grantee in the News: Kristine Yaffe on strategies for maintaining cognitive health in New York Times' New Old Age column

  On March 1, 2019, The New York Times’ New Old Age column featured insights of AFAR expert Kristine Yaffe, MD in an article cautioning the use of supplements to maintain cognitive health and possibly prevent dementia and Alzheimer’s. Dr. Yaffe is a 2001 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar. Read the article--”Supplements Won’t Prevent Dementia. But These Steps Might.”--here.  


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