News
News

The latest updates from AFAR.

Grantee in the News: Todd Cohen ‘s latest Alzheimer’s research in Cell Reports

Aug 31
2017

Grantee in the News: Todd Cohen ‘s latest Alzheimer’s research in Cell Reports

On August 29, 2017, Cell Reports published research by 2015 New Investigator Awards in Alzheimer's Disease recipient, Todd Cohen, PhD. In a first-of-its-kind study, Cohen and his team at the University of North Carolina show how a damaging cascade of events inside brain cells – and related to Alzheimer’s disease – can be stopped or reversed. The study, The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology, examined human cell cultures to show how amyloid beta can trigger a dramatic inflammatory response in immune cells and how that interaction damages neuron and leads to the formation of bead-like structures filled…


View MoreREAD MORE


Board Member in the News: Nir Barzilai gives TEDMED talk on Metformin and TAME Trial

Aug 29
2017

Board Member in the News: Nir Barzilai gives TEDMED talk on Metformin and TAME Trial

On August 29, 2017, TEDMED published a blog and talk by 1997 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar, 1994 AFAR Research Grant recipient, and AFAR Deputy Scientific Director Nir Barzilai, MD. In the TEDMED talk, Can we grow older without growing sicker?, Dr. Barzilai explores the prevalence of age-related diseases, the diversity of longevity in centenarians, and how, if the FDA moves to consider aging an indication, drugs like Metformin and Rapamycin have the potential to target aging and extend years of health. He poses: “What if we spent 80 years to get to the biological age of 60?…


View MoreREAD MORE


Board Members in the News: Caroline Blaum and Steven Austad on SIRIUSXM’s Doctor Radio program

Aug 29
2017

Board Members in the News: Caroline Blaum and Steven Austad on SIRIUSXM’s Doctor Radio program

On September 7, 2017, from 3-4pm EST, SIRIUSXM’s Doctor Radio Reports program will feature Scientific Director Steven Austad, PhD and Deputy Medical Officer Caroline Blaum, MD. Caroline Blaum, MD will share perspectives on geriatric care and Steven Austad, PhD will share insights on biomedical research on healthy aging. The program is hosted by former NBC News anchor Perri Peltz. The segment will air again on September 8th at 10am, September 9th at 6pm, and September 10th at 8pm EST. Steven N. Austad, PhD is a Distinguished Professor and Department Chair at the University of Alabama, Birmingham. Dr. Austad…


View MoreREAD MORE


Grantee in the News: Valter Longo on Fasting in WRVO Public Media

Aug 24
2017

Grantee in the News: Valter Longo on Fasting in WRVO Public Media

On August 19, 2017, WRVO Public Media, a member station of National Public Radio, produced a podcast and published an article featuring 1998 AFAR Research Grant and 2013 Vincent Cristofalo Rising Star Award in Aging Research recipient, Valter Longo, PhD. In the article and podcast episode, Why fasting can help, or hurt, your chances of longevity and weight loss, Dr. Longo shares insights on the three most common fasting practices, the short and long term effects of fasting, and how to incorporate fasting into one’s diet and lifestyle. With regard to diets that restrict eating to a period of 11 to 12 hours a…


View MoreREAD MORE


Grantees in the News: James Kirkland and Nathan LeBrasseur on senescent cells and bone loss in Nature Medicine and Cosmos

Aug 22
2017

Grantees in the News: James Kirkland and Nathan LeBrasseur on senescent cells and bone loss in Nature Medicine and Cosmos

On August 21, 2017, Nature Medicine published research from AFAR President-elect and 2012 Glenn/AFAR Breakthroughs in Gerontology Award recipient James Kirkland, MD and 2002 Glenn/AFAR Scholarships for Research in the Biology of Aging recipient Nathan LeBrasseur, PhD on the link between senescent cells and bone loss. The study, Targeting cellular senescence prevents age-related bone loss in mice, treated older mice with two senolytic compounds once a month for four months. The researchers found that the mice experienced a 30% increase in their bone volume and the structure of their bone revealed new deposition of bone tissue, resulting in increased strength. In a related…


View MoreREAD MORE


AFAR in the News: UK’s Sunday Times podcast explores innovations in aging research

Aug 22
2017

AFAR in the News: UK’s Sunday Times podcast explores innovations in aging research

On August 21, 2017, the UK-based national publication, The Sunday Times, produced a podcast and published the first of a two-part series of articles on innovations in aging research. The podcast, Danny in the Valley, focuses on Inside Silicon Valley’s quest to defeat ageing and features several AFAR experts sharing insights on the momentum in biotechnology and drug interventions that build off knowledge on the basic biology of aging. Early in the podcast, AFAR Executive Director Stephanie Lederman, EdM reflects on the early days of the field, and the revolutionary potential of the AFAR-managed TAME Trial. She shares: “I…


View MoreREAD MORE


AFAR in the News: IAGG World Congress multi-media spotlights AFAR experts

Aug 21
2017

AFAR in the News: IAGG World Congress multi-media spotlights AFAR experts

As a co-host of the 21st International Association of Gerontology and Geriatrics (IAGG) World Congress, AFAR is pleased to share multi-media highlights featuring AFAR experts, including special video content from IAGG TV, as well as slides from various presentations, such as the AFAR-sponsored morning plenary session on targeting aging. First, footage of the World Congress Opening Ceremony is available, featuring Board Member Mark Collins accepting an award on behalf of Paul Glenn, founder of AFAR’s long-time collaborator, the Glenn Foundation for Medical Research. In a special IAGG TV channel, former AFAR Board President and incoming President of IAGG…


View MoreREAD MORE


AFAR in the News: Australian publication Cosmos spotlights the TAME Trial and age-targeting drugs

Aug 17
2017

AFAR in the News: Australian publication Cosmos spotlights the TAME Trial and age-targeting drugs

On August 14, 2017, the Australian publication Cosmos featured 1997 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar, 1994 AFAR Research Grant recipient, and AFAR Deputy Scientific Director Nir Barzilai, MD and 2007 Glenn/AFAR Breakthroughs in Gerontology (BIG) Award winner Matt Kaeberlein, PhD. The article, Going to trial: anti-ageing pills, details the AFAR-managed Targeting Aging with Metformin (TAME) trial and Dr. Kaeberlein’s Dog Aging Project. Dr. Barzilai tells Cosmos: “If the trial ends up the way we except, that should be enough for the FDA to accept aging per se as a treatable indication.” Read the full…


View MoreREAD MORE


Grantee in the News: James Galvin on Alzheimer's disease prevention strategies in JAGS

Aug 17
2017

Grantee in the News: James Galvin on Alzheimer's disease prevention strategies in JAGS

On August 2, 2017, the Journal of the American Geriatrics Society (JAGS) published research from 2002 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar James E. Galvin MD, MPH. The study, Prevention of Alzheimer's Disease: Lessons Learned and Applied, looked at 19 studies about various brain-stimulating activities that may lower risks for Alzheimer’s disease. Dr. Gavin found that doing crossword puzzles, playing card games, using a computer, making arts or crafts, taking classes, having group discussions, listening to music, and exercising all had protective effects against Alzheimer’s disease. Read the full study in JAGS here. The…


View MoreREAD MORE


Grantee in the News: Dena Dubal on klotho and cognitive function in Cell Reports and Popular Science

Aug 10
2017

Grantee in the News: Dena Dubal on klotho and cognitive function in Cell Reports and Popular Science

On August 8, 2017, Cell Reports published research from 2015 AFAR Research Grant for Junior Faculty recipient, 2009 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar, and 1998 Glenn/AFAR Scholarships for Research in the Biology of Aging recipient Dena Dubal, MD, PhD. The study, Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice, tested young mice, aged mice, and mice genetically altered to have brains similar to people with Alzheimer’s or Parkinson’s disease. These mice were injected with a portion of the hormone klotho. The researchers found…


View MoreREAD MORE


AFAR mourns the passing of entertainer  Glenn Campbell after his courageous battle with Alzheimer’s disease.

Aug 09
2017

AFAR mourns the passing of entertainer Glenn Campbell after his courageous battle with Alzheimer’s disease.

The Campbell family exemplified compassionate advocacy in raising public awareness for the need for research and support for this devastating, age-related disease. AFAR will remember the Campbell family’s commitment as we continue to support research to better understand Alzheimer’s and related dementias.


View MoreREAD MORE


Board Member in the News: Nir Barzilai on genes and centenarians in ELLE India

Aug 08
2017

Board Member in the News: Nir Barzilai on genes and centenarians in ELLE India

On August 2, 2017, ELLE India featured 1997 Paul B. Beeson Emerging Leaders Career Development Award in Aging scholar, 1994 AFAR Research Grant recipient, and AFAR Deputy Scientific Director Nir Barzilai, MD. The article, World’s oldest people credit drinking and eating junk as the secret to a long life, looks closely at the different lifestyles of 11 centenarians. Dr. Barzilai suggests that genes play a very large role in becoming a centenarian. He shares: “Genetic factors are more dominating (than lifestyle factors) at exceptional older ages. In our (study of) centenarians, almost 50 per cent were obese or overweight, smokers, and not exercising…


View MoreREAD MORE


Board Member in the News: Steven Austad on male dominance in the scientific community

Aug 08
2017

Board Member in the News: Steven Austad on male dominance in the scientific community

On August 4, 2017, Mashable featured insights from AFAR Scientific Director Steven N. Austad, PhD, on the concept that clinical trials predominantly focus on men. The article, 9 ways science has been totally sexist, and totally wrong, outlines some of the many examples science have excluded or discriminated against women, such clinical trials: Dr. Austad shares: "Let's face it, everyone in the biomedical community has spent their lives studying one sex or the other. And it's usually males.” Read the full article here. Steven N. Austad, PhD, is a Distinguished Professor and Department Chair at the University of Alabama, Birmingham…


View MoreREAD MORE


Awardee in the News: Dongsheng Cai’s research on Hypothalamus Stem Cells & Aging in Nature and Futurism

Aug 07
2017

Awardee in the News: Dongsheng Cai’s research on Hypothalamus Stem Cells & Aging in Nature and Futurism

On August 3, 2017, Nature published research by 2017 Vincent Cristofalo Rising Star Award in Aging Research winner Dongsheng Cai, MD, PhD. Dr. Cai and scientists at Albert Einstein College of Medicine have found that stem cells in the brain’s hypothalamus govern how fast aging occurs in the body. The finding, made in mice, could lead to new strategies for warding off age-related diseases and extending lifespan. In a related press release, Dr. Cai states: “Our research shows that the number of hypothalamic neural stem cells naturally declines over the life of the animal, and this decline accelerates aging,…


View MoreREAD MORE


Grantee in the News: Jason Karlawish MedPageToday video on what’s needed, next in AD research

Aug 04
2017

Grantee in the News: Jason Karlawish MedPageToday video on what’s needed, next in AD research

On July 31, MedPageToday featured video commentary by 2007 Paul B. Beeson Emerging Leaders Career Development Award in Aging recipient Jason Karlawish, MD. Dr. Karlawish addresses the need to learn from the failures of past Alzheimer’s disease research and realistically approach both prevention and living with cognitive decline. He shares: "The way forward is more research, but it's research that has to be smart and learns from those failures...It's a complicated disease. There are many pathologies involved on top of an aging brain. But I think the signals from our studies are telling us that we…


View MoreREAD MORE


Grantee in the News: NPR broadcasts Anne Brunet lecture on Atlas of Aging

Aug 04
2017

Grantee in the News: NPR broadcasts Anne Brunet lecture on Atlas of Aging

On July 31, NPR affiliate WCAI broadcast a lecture that 2005 AFAR Research Grant recipient Anne Brunet, PhD gave at the Marine Biological Laboratory of the University of Chicago. Dr. Brunet provided an overview of the insights we’ve gained and questions yet to be answered on the biological processes of aging: “The great challenge of the field is to understand all the changes in all different tissues and cell types; almost like having an atlas of aging,” she said. Listen to the lecture here. Anne Brunet, PhD is a professor of genetics and co-director of the Paul…


View MoreREAD MORE


Board member in the News: Thomas Rando on Biomarkers of Aging in Wired

Aug 03
2017

Board member in the News: Thomas Rando on Biomarkers of Aging in Wired

On July 28, 2017, Wired.com featured commentary by AFAR Board Member and two-time grantee Thomas Rando, MD, PhD in an article exploring Silicon Valley’s push to accelerate longevity biotechnology through biomarkers in blood. The article, A Search for Anti-Aging Secrets Starts with the Blood of 600 Estonians, explored the private company BioAge’s goal of measuring biological age using signals--or biomarkers-- floating in a drop of blood. Dr. Rando lends expert commentary: “Reliable biomarkers would greatly accelerate this whole field,” says Tom Rando, who directs Stanford’s Glenn Center for the Biology of Aging and first…


View MoreREAD MORE


Board member in the News: Rudy Tanzi on Brain Microbiomes and AD in Forbes

Aug 03
2017

Board member in the News: Rudy Tanzi on Brain Microbiomes and AD in Forbes

  A July 28, 2017 article on Forbes.com spotlights the Brain Microbiome Project led by AFAR board member Rudolph “Rudy” Tanzi, PhD. The article, Mapping The Brain's Microbiome: Can Studying Germs In The Brain Lead To A Cure For Alzheimer's?, explains: Harvard researchers, Dr. Rudolph Tanzi and Robert D. Moir, PhD, are heading up a team, funded by the Cure Alzheimer’s Fund and the Good Ventures Foundation, that has taken on mapping the microbiome, the population of microorganisms, some helpful and some pathological, that exists inside the brain. The monumental task, dubbed The Brain Microbiome…


View MoreREAD MORE


AFAR presents Irving S. Wright and Vincent Cristofalo Awards

Aug 01
2017

AFAR presents Irving S. Wright and Vincent Cristofalo Awards

On Tuesday July 25, AFAR presented its 2017 Scientific Awards in a special ceremony at the 21st annual IAGG World Congress in San Francisco. AFAR Scientific Director Steven N. Austad, PhD, hosted the event, which included lectures from each awardee followed by a reception. Mark S. Lachs MD, MPH, co-chief of the Division of Geriatrics and Palliative Medicine and a professor of medicine at Weill Cornell Medicine, received the Irving S. Wright Award of Distinction. This award is named in honor of AFAR’s founder and recognizes exceptional contributions to basic or clinical research in the field of aging. Established in 1982,…


View MoreREAD MORE


AFAR honors Architects of Aging at Biotechnology Luncheon in San Francisco

Aug 01
2017

AFAR honors Architects of Aging at Biotechnology Luncheon in San Francisco

  On Tuesday, July 25, AFAR hosted a luncheon symposium and awards ceremony, The Architects of Aging, in San Francisco, where we honored leaders in biotechnology and healthspan.   Nearly 100 guests took in breathtaking views from the 32nd floor of the Westin St. Francis.   After AFAR Executive Director Stephanie Lederman and Scientific Director Steven N. Austad, PhD, introduced the program, AFAR presented its Honorary Leadership Award to Nathaniel “Ned” David (Co-Founder and President - Unity Biotechnology) and its Chairman’s Award to Edward Lanphier (Founder - Sangamo Therapeutics, Inc.). Both awardees spoke passionately about how biotechnological interventions…


View MoreREAD MORE


AFAR presents Irving S. Wright and Vincent Cristofalo Awards

Aug 01
2017

AFAR presents Irving S. Wright and Vincent Cristofalo Awards

On Tuesday July 25, AFAR presented its 2017 Scientific Awards in a special ceremony at the 21st annual IAGG World Congress in San Francisco. AFAR Scientific Director Steven N. Austad, PhD hosted the event, which included lectures from each awardee followed by a reception. Mark S. Lachs M.D., M.P.H., co-chief of the Division of Geriatrics and Palliative Medicine and a professor of medicine at Weill Cornell Medicine, received the Irving S. Wright Award of Distinction. This award is named in honor of AFAR’s founder and recognizes exceptional contributions to basic or clinical research in the field of…


View MoreREAD MORE




BACK TO TOPBACK TO TOP