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AFAR Grantees in the News: New research on CytoTape cell recording tool co-authored by Grantees Denise Cai, PhD, and Changyang Linghu, PhD, published in Nature

AFAR Grantees in the News: New research on CytoTape cell recording tool co-authored by Grantees Denise Cai, PhD, and Changyang Linghu, PhD, published in Nature

On January 26th, 2026, Nature published new research co-authored by AFAR Grantees Denise Cai, PhD, and Changyang Linghu, PhD, on a new tool developed with AI to analyze cellular processes over time and at scale by recording cell activity continuously for weeks without disrupting normal cell function.

“Unraveling the mysteries of how biological organisms function begins with understanding the molecular interactions within and across large cell populations. A revolutionary new tool, CytoTape, acts as a sort of tape recorder produced and maintained by the cell itself, enabling scientists to rewind back in time and view interactions on a large scale and over long periods of time,” a related University of Michigan press release explains.

Dr. Cai is a 2023 McKnight Brain Research Foundation Innovator Awards in Cognitive Aging and Memory Loss recipient.

Dr. Linghu is a 2024 Glenn Foundation for Medical Research Grants for Junior Faculty recipient.

Read the original Nature article, “Scalable and multiplexed recorders of gene regulation dynamics across weeks”, here.

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