Kishore Kuchibhotla
Kishore Kuchibhotla - PhD
AFAR Research Grants for Junior Faculty - 2018
Kishore Kuchibhotla

Kishore Kuchibhotla - PhD

Assistant Professor - Johns Hopkins University
Maryland, USA


AFAR Research Grants for Junior Faculty - 2018

Improving cognitive flexibility in aging by modulating context-dependent neural circuits

A gradual and steady loss of cognitive flexibility is a part of the healthy aging process. Older adults go through periods of confusion even when there is no overt dementia or disease. However, there are also episodes of lucidity in which individuals show improved cognitive flexibility. In the proposed research, Dr. Kishore Kuchibhotla will seek to uncover the brain mechanisms that enable context-dependent improvements in lucidity during aging. Using a mouse model of aging, Dr. Kuchibhotla will observe and then control the neurons responsible for regulating context in order to discover if cognitive flexibility is “lost” with aging or if it is lying dormant within underlying neural circuitry. The goal of Dr. Kuchibhotla’s research is unlock high-performance behavioral modes in the healthy aging brain by manipulating neural circuitry and to provide novel ways to extend healthy brain function.

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