2019 Grant Recipients

 

Biology of Aging Grants
 

Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty


Glenn Foundation for Medical Research Breakthroughs in Gerontology (BIG) Award
 

Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research
 

Kalman/AFAR Scholarships for Research in the Biology of Aging


The Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging

 

Physician Training Grants

 

The Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76)

 

Medical Student Training in Aging Research (MSTAR) Program

 


 

Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty

Carlos Aguilar, PhD, Assistant Professor: University of Michigan: Deconstructing stem cell aging through interact-omics
Nausica Arnoult, PhD, Assistant Professor, University of Colorado Boulder: DNA Double Strand Break repair pathway choice and repair fidelity during cellular and organismal aging
Abigail Buchwalter, PhD, Assistant Professor, University of California, San Francisco: Defining drivers and consequences of ribosome biogenesis deregulation during mammalian aging
Lindsay De Biase, PhD, Assistant Professor, David Geffen School of Medicine at UCLA: Regional differences in microglial lysosome function: implications for microglial aging and cognitive decline
Brian DeBosch, MD, PhD, Assistant Professor, Washington University School of Medicine: Activating the hepatic glucose fasting response to attenuate aging-related metabolic and autophagic defects.
Yarui Diao, PhD, Assistant Professor, Duke University School of Medicine: Identification and application of cis-regulatory enhancer elements for muscle stem cell function and muscle regeneration in aging.
Sung Min Han, PhD, Assistant Professor, University of Florida: Identifying genes that regulate mitochondrial positioning at the synapse during aging
Mark McCormick, PhD, Assistant Professor, University of New Mexico Health Sciences Center: Measurement of the conservation in mammalian cells of the effects of lifespan-extending tRNA synthetase inhibitors.
Maria Mihaylova, PhD, Assistant Professor, The Ohio State University: Understanding the Effects of Dietary and Microbially Derived Metabolites on Gut Epithelial and Immune Cell Homeostasis During Aging
A. Hunter Shain, PhD, Assistant Professor, University of California, San Francisco: Somatic mutation burden and aging in human skin
Aakanksha Singhvi, PhD, Assistant Member, Fred Hutchinson Cancer Research Center, University of Washington: Molecular investigation of glial roles in neural aging
Peter Sudmant, PhD, Assistant Professor, University of California, Berkeley: Ultra-sensitive profiling of cell-type specific age-associated somatic mitochondrial mutational diversity
George Sutphin, PhD, Assistant Professor, University of Arizona: Understanding the interplay between tryptophan and NAD metabolism during aging
Ming Xu, PhD, Assistant Professor, University of Connecticut Health Center, Targeting p21high senescent cells to improve healthspan and lifespan

 

Glenn Foundation for Medical Research Breakthroughs in Gerontology (BIG) Award

Ursula Jakob, PhD, Professor, University of Michigan: Role of early epigenetic events in stress resistance and lifespan
Norbert Perrimon, PhD, Professor of Genetics Blavatnik Institute, Harvard Medical School: Regulation of the aging process by molecules and pathways involved in organ communication

 

Glenn Foundation for Medical Research Postdoctoral Fellowships in Aging Research

Laura Bott, PhD, Postdoctoral Fellow, Northwestern University: Elucidating intra- and inter-individual variability in proteostasis network capacity during aging
Nirmalya Dasgupta, PhD, Postdoctoral Associate, Sanford Burnham Prebys Medical Discovery Institute: A role for histone chaperone HIRA in cytoplasmic DNA sensing and senescence-associated inflammatory signaling
Yoko Henderson, PhD, Postdoctoral Research Fellow, Cleveland Clinic Lerner Research Institute: Determining the effects of late-life initiated caloric restriction on aging-related cognitive decline, frailty, and H2S production
Ryo Higuchi-Sanabria, PhD, Postdoctoral Fellow, University of California, Berkeley: More than just a load control: cytoskeletal form and function during aging
Li Li, MD, PhD, Postdoctoral Scholar, Stanford University: A mitochondrial membrane-spanning ternary complex is a drug target for aging and Parkinson's disease
Elise Marsan, PhD, Postdoctoral Fellow, University of California, San Francisco: Glial dysfunctions in brain aging and neurodegenerative diseases
Mikolaj Ogrodnik, PhD, Research Fellow, Mayo Clinic: Targeting lipid metabolism to reduce pro-inflammatory phenotype and viability of senescent cells
Seungjin Ryu, PhD, Postdoctoral Associate, Yale University: The role of a matricellular adipokine in aging by integration of immune-metabolic response
Kevin Stein, PhD, Postdoctoral Scholar, Stanford University: Defining the role of co-transitional proteostasis in aging and age-related pathologies
Matthew Ulgherait, PhD, Postdoctoral Researcher, Columbia University: Engineering the microbiome to ameliorate age-related intestinal diseases and extend lifespan in Drosophila

AFAR is grateful to the Glenn Foundation for Medical Research for their support of and collaboration on the above grant programs.


 

The Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging

Priya Balasubramanian BVSc, PhD, Postdoctoral Research Associate, University of Oklahoma Health Sciences Center: Role of endothelial senescence on age-related cognitive decline
Chia-Wei Cheng, PhD, Postdoctoral Fellow, Massachusetts Institute of Technology: Impact of fasting and ketone bodies on intestinal stem cell in aging
Miranda Cullins, PhD, Postdoctoral Fellow, University of Wisconsin-Madison: Effects of age and exercise on lingual neuromuscular plasticity and swallowing function after stroke
David Gate, PhD, Postdoctoral Fellow, Stanford University: Antigen identification of clonally expanded T cells in aging cerebrospinal fluid
Alice Kane, PhD, Postdoctoral Fellow, Harvard Medical School: Development of a predictive healthspan and lifespan clock to accelerate preclinical studies
Jia Nie, PhD, Postdoctoral Fellow, University of Texas Health at San Antonio: Effect of Aging and mTOR Inhibition on Islet Cell Molecular Profiling
Matthew Yousefzadeh, PhD, Researchers 6 (Postdoctoral Fellow), University of Minnesota: Immune-specific aging drives senescence and dysfunction of peripheral tissues

 

Kalman/AFAR Scholarships for Research in the Biology of Aging

Jenna Blujus, University of Wisconsin-Milwaukee: Memory-Based Viewing: A Potential Non-Invasive Marker of Medial Temporal Lobe Integrity
Jeongmoon Choi, Georgia Institute of Technology: Exploiting circulating juvenile protective factors using heterochonic parabiosis
Hui Jean Kok, University of Florida: The role of IGF-I in satellite cells and skeletal muscle regeneration
Daniel Matasic, University of Iowa: Aging & Arrhythmias: Metabolic Regulation of the Cardiac Sodium Channel
Kenyaria Noble, Medical University of South Carolina: Contributions of Immune Cell Dysfunction to Age-Related Hearing Loss
Katarzyna Piekarz, University of Oklahoma Health Sciences Center: Revealing the mechanisms behind age-related alpha motor neuron loss and how to prevent it
Sarah Royer, University of California, Irvine: The novel role of C1q in inhibiting neurogenesis within the aged brain
Yao Tong, Tulane University: Characterization of RPE Cell Death Induced by 4-HNE in Age-related Macular Degeneration
Mariana Uchoa, University of Southern California: Inteleukin-10 induced metabolic changes in macrophages exposed to Amyloid-beta
Ruofan Yu, Baylor College of Medicine: Identification of Molecular Mechanisms Behind HDA-mediated Aging and Stress Response

 


 

The Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76)

The 2019 Beeson Scholars are fully funded through the National Institute on Aging (NIA) of the National Institutes of Health (NIH)

Elizabeth Goldberg, MD, Associate Professor, The Alpert Medical School of Brown University: GAPcare II: The Geriatric Acute & Post-Acute Care Coordination Program for Fall Prevention in the Emergency Department
Meredith Greene, MD, Assistant Professor, University of California San Francisco: Tailored Geriatric Assessment and Management for HIV Care Settings
Lisa Kilpela, PhD, Assistant Professor, University of Texas Health Science Center San Antonio: Binge Eating Spectrum Treatment in Older Women (BESTOW): An Investigation and Intervention-Tailoring Project
Allison Magnuson, DO, Assistant Professor, University of Rochester: Mitigating Cancer-Related Cognitive Dysfunction in Older Adults with Breast Cancer
Zachary Marcum, PharmD, PhD, Assistant Professor, University of Washington: Antihypertensives and the Aging Brain
Rowena McBeath, MD, PhD, Assistant Professor, Jefferson University: In Vivo Model of Human Enthesis Regeneration
Veerawat Phongtankuel, MD, Assistant Professor of Medicine, Joan & Sanford I. Weill Medical College of Cornell University: Developing and piloting a multi-component technology-based care intervention to address patient symptoms and caregiver burden in home hospice.
Jason Roh, MD, Staff Physician, Massachusetts General Hospital: Activin Type II Receptor Activity in Age-related Frailty and Heart Failure
Matthew Schrag, MD, PhD, Assistant Professor, Vanderbilt University School of Medicine: Defective Lysosomal Membrane Fission Mediates Axonal Lysosome Accumulation in Dystrophic Neurites in Alzheimer's Disease.
Victoria Lai-Yen Tang, MD, Assistant Professor, University of California, San Francisco: Improving Outcomes of Older Adults with Psychosocial Vulnerability Undergoing Major Surgery
Melisa Wong, MD, MAS, Assistant Professor, University of California, San Francisco: Advancing Patient-Centered Decision Making in Older Adults with Lung Cancer: Incorporating Risk of Functional Decline into Treatment Discussions
Heidi Zapata, MD, PhD, Assistant Professor, Yale School of Medicine: NLRP3 Inflammasome Activation and Mitochondrial Function in the Setting of Aging and HIV Infection

 


 

Medical Student Training in Aging Research (MSTAR) Program

MSTAR Students Privately Funded at Weill Cornell Medical College

Fatima Nathalia Morales Delgado, Weill Cornell Medicine
Anthony Palillo, Weill Cornell Medicine
Yushan Pan, Weill Cornell Medicine
Carrie Sha, Weill Cornell Medicine





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