The Irene Diamond Fund/AFAR Postdoctoral Transition Awards in Aging for 2018

Bumsoo Ahn

Bumsoo Ahn

Postdoctoral Fellow, Oklahoma Medical Research Foundation


Unacylated ghrelin as a therapeutic strategy for age-associated skeletal muscle weakness The age-related progressive loss of muscle mass and contractile dysfunction, sarcopenia, universally affects the elderly leading to frailty, reduced quality of life and health span. However, there are no pharmacological therapies to treat sarcopenia. In the proposed study, Dr. Bumsoo Ahn will investigate if...

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Jenna Bartley

Jenna Bartley

Postdoctoral Fellow, University of Connecticut School of Medicine


The effect of metformin on influenza vaccine responses and T cell function in the elderly With age, cell-mediated immune responses are diminished, which leads to an increased susceptibility to infection and poor vaccination responses. Dr. Bartley’s current research investigates how changes in the cellular metabolism of T cells influence these alterations, particularly in...

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John Collins

John Collins

Postdoctoral Fellow, University of North Carolina at Chapel Hill


SIRT6 as a novel therapeutic target in aging and osteoarthritis Osteoarthritis (OA) is a leading cause of disability that affects over 30 million adults in the United States.  The major risk factor is aging. There are currently no disease-modifying treatments for OA and the exact mechanisms how aging contributes to the development of OA remains...

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Troy Cross

Troy Cross

Senior Research Fellow, Mayo Clinic


The neural origins of exercise intolerance in the aging human: implications for widening the healthspan With age, it becomes progressively more difficult to perform and engage in regular physical activity. This difficulty may be due to an increasing intensity of symptoms of like breathlessness and fatigue. In the proposed research, Dr. Troy Cross will investigate...

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Shelli Farhadian

Shelli Farhadian

Instructor, Yale University School of Medicine


Neuroinflammation in older adults with HIV: A single cell approach While advances in antiretroviral therapy (ART) have decreased rates of HIV-associated dementia, the prevalence of all neurocognitive disorders in adults with HIV has not changed. 50% of adults with HIV on ART have some form of neurocognitive impairment. Chronic HIV is associated with persistent immune activation...

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Amy Gleichman

Amy Gleichman

Postdoctoral Fellow, University of California Los Angeles


Astrocytic regulation of synapse formation and elimination in aged mice after stroke Stroke is a leading cause of death and disability. However, few treatment options exist to enhance stroke recovery. While significant progress is being made to understand molecular changes from stroke, most of the studies use young adult animals. This removes age-related variables, and...

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Claire Gustafson

Claire Gustafson

Postdoctoral Fellow, Stanford University


T Follicular Helper Cells in Mucosal Immune Aging As we age, mucosal sites, i.e. surfaces that are in contact with the external environment, become increasingly susceptible to infections such as flu and pneumonia. However, little is known about what causes the decline in mucosal immune protection during aging. In the proposed research, Dr. Claire...

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Emilie Reas

Emilie Reas

Postdoctoral Fellow, University of California San Diego


Association between Blood-Brain Barrier Braekdown and Brain Microstructure in Mild Cognitive Impairment In the proposed research, Dr. Emilie Reas will examine whether the blood-brain barrier (BBB) breaks down in the early stages of Alzheimer’s Disease (AD) and how BBB permeability changes over the course of AD. The BBB filters toxins and other substances...

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