Ming Xu
Ming Xu - PhD
Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty - 2019
Ming Xu

Ming Xu - PhD

Assistant Professor - University of Connecticut Health Center
Connecticut, USA


Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty - 2019

Targeting p21high senescent cells to improve healthspan and lifespan

Dr. Xu plans to examine the role of senescent cells in aging as well as to develop and test the effects of senolytic drugs (which specifically kill senescent cells) for translational purpose. Dr. Xu hopes that these studies will provide us and others with important information about the role of cellular senescence in aging, which may lead to future clinical trials using these drugs to slow down the effects of aging in humans. In this project, Dr. Xu will use his novel mouse model to test the role of p21-highly-expressed (p21high) senescent cells in aging, and examine the underlying mechanism by which these cells lead to tissue dysfunction.

View all grantees for Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty in 2019

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