Jenna Galloway
Jenna Galloway - PhD
AFAR Research Grants for Junior Faculty - 2015
Jenna Galloway

Jenna Galloway - PhD

Assistant Professor - Massachusetts General Hospital
Massachusetts, United States


AFAR Research Grants for Junior Faculty - 2015

Tendon cell homeostasis and stem cell activity during growth, adulthood and aging in the mouse

Tendons are an integral part of our everyday movements, transmitting the force produced by the muscle to the bone. As we age, our tendons become more prone to degenerative conditions and injury, and their healing capacity diminishes. Tendon and ligament injuries are thus very common in an aging population, affecting the quality of life and mobility of millions of people in the United States each year (and incurring significant healthcare costs). But with limited knowledge of the cellular changes that occur as a tendon ages, it is difficult to design therapies to address age-related decline.

Dr. Galloway and her group are studying the cellular aspects of tendon aging in a transgenic mouse model. The group’s goal is to learn key differences in the activities of young, adult, and aged tendon cells in normal and injured conditions.

Those discoveries will allow Dr. Galloway and her group to better understand the mechanisms of aging in tendon tissues—namely, why aged tendons decline in their ability to cope with the stress of daily activities and to heal from acute injuries. Dr. Galloway hopes their work will help make an impact on age-related tendon injuries and degeneration.

View all grantees for AFAR Research Grants for Junior Faculty in 2015

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