2025

Hevolution/AFAR New Investigator Awards in Aging Biology and Geroscience Research


Snyder Mackler Headshot crop

Noah Snyder-Mackler, PhD

Associate Professor, Arizona State University

Molecular causes and consequences of inter- and intra-individual heterogeneity in aging

Aging is inevitable, but it doesn't affect us all in the same way. There's substantial variation in how individuals age, but we still don’t fully understand what drives this heterogeneity at a molecular level. Dr. Snyder-Mackler aims to uncover the molecular factors that contribute to variation in aging within and across individuals in a shorter-lived, but highly human-relevant species: rhesus macaques. His research combines high throughput molecular data with statistical methods to identify molecular changes that may cause aging. He will then test if these causal molecular changing are important for health and survival. By identifying these age-related molecular markers, this research could lead to better insights into aging and inform strategies for improving health and longevity in the future.

More 2025 Recipients of this Grant

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Weishan Huang, PhD

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Emma Johnson, PhD

Elucidating environmental context-dependent genetic variation related to aging and lifespan in humans

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Hongjie Li, PhD

Building Systematic Brain-Body Communication and Personalized Aging Trajectories

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Katharina Maisel, PhD

Investigating changes in the physical environment in the lymph node that alter immune cell functions in aging

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Inflammaging in the Lung: Dissecting the Impact of Aging on pulmonary vs. circulatory factors

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Jason Sheltzer, PhD

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