The Role of Neuronal Glycolysis in the Aging Motor Circuit
Motor learning is a process that allows us to adapt and interact with our environment, and it is critical throughout our lifespan. However, a decrease in our ability to perform this kind of learning has been documented with age. Dr. Carmone's lab aims to examine why neurons of the motor system are no longer capable of supporting this type of learning. They will focus on cellular metabolism which is particularly important in supporting energy demanding processes like learning. More specifically, they are working on examining the contribution of glycolysis, a central metabolic pathway, to motor behavior and learning with age.