Advancing Research
by funding Grant Programs and Fellowships
Driving Innovation
by guiding studies such as the FAST Initiative, the SuperAgers Initiative, and the TAME Trial
Furthering the Field
by supporting the infrastructure of three NIA Initiatives and leading the Amplifying Geroscience Initiative.
Top Breakthroughs driven by AFAR Experts
Delaying Disease by Targeting Aging
Saving Costs by Extending Healthspan
What are the Hallmarks of Aging?
What is Geroscience?
What is the Longevity Dividend?
Dr. Chan’s project which aims to regenerate cartilage to reverse osteoarthritis, is co-funded by AFAR and the Arthritis National Research Foundation. Dr. Chan’s lab looks specifically at the skeletal stem cell (SSC) and whether it is possible to reactivate the body’s own SSCs to regenerate lost cartilage by restoring the stem cell microenvironment or “niche.” If one could restore the SSC’s “niche” with specific factors, it could also lead to better stem cell function, including formation of lost tissues. This approach may also work for other types of tissues such as heart, brain, skin, or muscles, which are all adversely affected by aging.
