Funding Opportunities
Funding Opportunities

Since 1981, AFAR has provided approximately $132 million to more than 2,800 talented investigators and students. To learn more about each grant, click below or contact the AFAR grant program staff at grants@afar.org

The New Investigator Awards in Alzheimer's Disease

 

The Program

Funded by The Rosalinde and Arthur Gilbert Foundation, the major goal of this partnership program is to support important research in areas in which more scientific investigation is needed to improve the prevention, diagnosis, and treatment of Alzheimer's disease. The program also serves to encourage junior investigators in the United States and Israel to pursue research and academic careers in the neurosciences, and Alzheimer's disease in particular.

Projects in basic and translational research related to Alzheimer's disease (AD) that are clinically relevant, will be considered. For one of the awards, priority may be given to an investigator with a research project that has high translational potential.

Examples of promising areas of research include, but are not limited to:

  • Genetic and environmental risk/protective factors
  • Cellular and molecular pathways
  • Cardiovascular and cerebrovascular factors
  • Neuro-inflammation
  • Neuroimaging and other biomarkers
  • Cellular, animal and in silico models
  • Diagnostic and prognostic markers
  • Exercise, nutrition, and dietary factors
  • Drug discovery  and other therapeutics

In addition, proposals will be accepted that relate to the basic mechanisms of central nervous system (CNS) aging, such as:

  • Learning and memory
  • The biology and pathobiology of synapses
  • Neurogenesis, neural and glial progenitors

It is anticipated that up to 3 grants of $100,000 each will be awarded in 2015. Applicants may propose to use the award over the course of one or two years as justified by the proposed research. Up to 8% of funds may be budgeted for overhead or indirect costs (not to exceed $7,407). Funding will begin July 1, 2015.

Eligibility

The applicant must be an independent investigator with independent research space as described in a form completed by the Dean or Department Chair, and must be no more than 10 years beyond start of postdoctoral research training as of July 1, 2015. Exceptions to the ten year rule may be requested for unusual circumstances by emailing an NIH-style biosketch to AFAR at grants@afar.org at least one week prior to the submission deadline. The proposed research must be conducted at any type of not-for-profit setting in the United States or Israel.

The New Investigator Awards in Alzheimer's Disease do not provide support for:

  • Postdoctoral fellows in the laboratory of a senior investigator
  • Investigators who have already received major extramural funding (such as an R01 or NSF equivalent grant) prior to and up until the start date of the award
  • Senior faculty, i.e. at the rank of Associate Professor level or higher
  • NIH Intramural program employees
  • Applicants who are conducting research at a for-profit institution, or at an institution outside of the United States or Israel

Applicants cannot apply for the 2015 AFAR Research Grant for Junior Faculty or the 2015 Glenn/AFAR BIG Program. Applications for this program will be considered for the AFAR Research Grant for Junior Faculty if deemed competitive.

Application Guidelines

Five criteria are used to determine the merit of an application:

  • Qualifications of the applicant;
  • Quality of the proposed research;
  • Relevance of the proposal to how mechanisms of aging may lead to AD or encourage healthy brain aging;
  • Excellence of the research environment;
  • Likelihood that the project will advance the applicant's career in Alzheimer's Disease

For one of the awards, priority may be given to an investigator with a research project that has great translational potential provided the application is deemed to meet the highest standards set by AFAR's Review Committee.

If you are using animals in your research, please review Principles of Animal Use for Gerontological Research.

Application Procedures

The deadline for receipt of all Letters of Intent is December 15, 2014 at 5:00 p.m. EST. Please refer to the New Investigator LOI instructions. Incomplete LOIs cannot be considered.  All Letters of Intent and Institutional Commitment Forms must be submitted through the website www.afar.org/grants.  The Letters of Intent will be reviewed by a committee.  Applicants will be notified by January 31, 2015, and a subset of applicants will be invited to submit a full application by March 18, 2015.

Click here for our Frequently Ask Questions page.

All LOI candidates who are invited to submit applications must have it endorsed by their institution. Final awards are announced by early June. The award start date is July 1, 2015. AFAR will not provide reviewer critiques to any applicants at any review level.

Reporting Requirements

Investigators will be required to submit a brief narrative report on the progress of their research five months after the start date of the award. Final narrative and financial reports are required within three months following the end date of the award.

Annual Meeting

The award recipients are expected to attend the AFAR Grantee Conference which convenes AFAR grant recipients, mentors and leaders in the field to review and disseminate the research progress of the grantees and their findings. The meeting encourages networking, facilitates collaborations, and enhances the development of leadership. In addition, grant recipients of the New Investigator Awards in Alzheimer's are expected to attend a special session at the grantee conference.

The Rosalinde and Arthur Gilbert Foundation

The Rosalinde and Arthur Gilbert Foundation (www.thegilbertfoundation.org) is committed to providing and connecting resources to organizations that promote and improve health, education, economic, and cultural opportunities to communities in California and Israel.

The Rosalinde and Arthur Gilbert Foundation supports:

  • College access and retention in Greater Los Angeles
  • Education, economic development, and scientific research & caregiver support
  • Diabetes prevention and Alzheimer's disease research & caregiver support
  • Cultural organizations and arts education programs in Greater Los Angeles
  • Jewish organizations in Greater Los Angeles
  • Programs at UC Berkeley and UCLA that intersect with the Foundation's mission and objects

In the area of Alzheimer's disease, The Rosalinde and Arthur Gilbert Foundation focuses its grantmaking on the advancement of research by junior investigators in the United States and Israel and investments in Alzheimer's disease caregiver resources and support.


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