2014

Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty


Jason Held, PhD

Assistant Professor, Washington University School of Medicine

Investigating the redox biology of aging in C. elegans

Dr. Held is interested in understanding how cellular signaling may have an effect on healthspan. He is particularly interested in the paradoxical role of reduction-oxidation (redox) processes in the biology of aging. He is developing technologies to identify specific protein signatures which sense changes in the oxidation status of cells. AFAR’s support will allow Dr. Held to develop and apply new analytical tools to provide a precise molecular readout of the protein targets activated by reactive oxygen species (ROS) and redox changes in cells.

More 2014 Recipients of this Grant

Alexander Soukas, MD, PhD

Dietary modulation of lifespan by target of rapamycin complex 2

View Profile
Christin Burd, PhD

Beyond cellular senescence: defining the meaning of p16INK4a expression in vivo

View Profile
Fabio Demontis, PhD

Translational Regulation of Selective Autophagy by 4E-BP during Muscle Aging in Drosophila

View Profile
Jason Butler, PhD

Rejuvenation of aged vascular niches to enhance hematopoietic function

View Profile
Jason Karpac, PhD

Inter-organ communication in the systemic control of aging

View Profile
Jason MacGurn, PhD

Molecular Mechanisms of Ubiquitin Homeostasis During Cellular Stress

View Profile
Subhash Katewa, PhD

Role of circadian clocks in mediating effects of Dietary Restriction on lifespan extension

View Profile
Ilya Finkelstein, PhD

High-Throughput Studies of Protein Homeostasis in Aging Cells

View Profile

< View All 2014 Grantees